Phytoestrogens in peri- and postmenopause
Despite increasing interest in alternative therapies for menopausal
hot flashes that avoid use of estrogens, the efficacy
and safety of other options currently are not well supported.
There is no conclusive evidence that phytoestrogen
supplements effectively reduce the frequency or severity of
hot flushes and night sweats in postmenopausal women.
Many of the studies are of poor quality and results are inconsistent.
In women who need relief for mild vasomotor
symptoms isoflavones can be tryed. Isoflavones are not
as effective as estrogens in relieving hot flashes.There is
a (proably weak) indication, but no conclusive evidence,
that isoflavones have a beneficial effect on bone health
and that there is an association between lifelong soyabean
intake und reduced risk of breast cancer.
Klinik und Poliklinik für Frauenheilkunde und Geburtshilfe,Köln
und Bernd Krause, Berlin
Foth D. Phytoestrogene ... Gynakol Geburtsmed Gynakol Endokrinol 2008; 4(3): 184-193 publiziert 30.11.08 www.akademos.de/gyn ©akademos Wissenschaftsverlag 2008 ISSN 1614-8533