In cooperation with

Abstract

Birth weight,gestational diabetes, and perinatal programming

During recent years, a new medical research topic called »perinatal programming« has been established, focussing on the pre- and neonatal »imprinting« of long-term increased dispositions for diseases. For the establishment of this new field, studies in offspring of women with diabetes during pregnancy as well as in later life of children with a low birth weight were crucial.These studies pointed towards permanent consequences of prenatal and/or neonatal exposures in the affected individuals in terms of increased risk of diabetogenic, adipogenic and atherogenic disturbances. Current research is focussing on causes and mechanisms of this prenatal and perinatal malprogramming.

CME Prakt Fortbild Gynakol Geburtsmed Gynakol Endokrinol 2009; 5(3): 182-192

Keywords
Prenatal imprinting, perinatal programming,gestational diabetes, small-baby-syndrome

Karen Schellong, Elke Rodekamp,Thomas Harder,
Joachim W. Dudenhausen, Andreas Plagemann
Arbeitsgruppe »Experimentelle Geburtsmedizin«,
Klinik für Geburtsmedizin, Charité - Universitätsmedizin Berlin,
Campus Virchow-Klinikum,Berlin
Reviewer: Christoph Bührer, Berlin
und Uwe Lang,Graz, Österreich

Schellong K. Geburtsgewicht ... Gynakol Geburtsmed Gynakol Endokrinol 2009; 5(3): 182-192 publiziert 30.11.09 www.akademos.de/gyn ©akademos Wissenschaftsverlag 2009 ISSN 1614-8533