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Abstract

Malignant diseases during pregnancy

One in 1000 pregnancies is complicated by the diagnosis of pregnancy-associated malignant diseases. Frequency and localisation are comparable to those of non pregnant women of the same age. In industrialised countries, the clear increase in the average age of first time pregnancies is connected to an increase in pregnancy-associated malignant diseases. The most frequently diagnosed are breast cancer, cervical cancer, melanoma, colorectal cancer, Hodgkin?s disease and leukaemia. There seems to be no difference in prognosis of malignant disease in pregnant compared to non-pregnant patients, if at it?s diagnosis, the stage of disease and the following therapy are comparable.

In most cases therapy in pregnant patients can be performed according to valid treatment standards. Close fetomaternal surveillance including serial Doppler recordings are necessary to recognize fetal impairment as early as possible.The delivery has to be scheduled accordingly to avoid life threatening consequences for mother and child.

CME Prakt Fortbild Gynakol Geburtsmed Gynakol Endokrinol 2016; 12(3): 82?98

Keywords
Malignant disease, pregnancy

Ines Schönborn1, Robert Armbrust2, Mustafa Zelal
Muallem2, Wolfgang Henrich1, Jalid Sehouli2
1 Klinik für Geburtsmedizin, Campus Virchow-Klinikum,
Charité – Universitätsmedizin Berlin, Berlin
2 Klinik für Gynäkologie, Campus Virchow-Klinikum,
Charité – Universitätsmedizin Berlin, Berlin
Reviewer: Tanja Fehm, Düsseldorf,
und Oumar Camara, Bad Langensalza

Schönborn I. Maligne ... Gynakol Geburtsmed Gynakol Endokrinol 2017; 13(1): 82–98 publiziert 31.03.2017 www.akademos.de/gyn ©akademos Wissenschaftsverlag 2017 ISSN 1614-8533