In cooperation with

Abstract

Hereditary breast and ovarian cancer – aspects of counseling

Genetic mutations cause up to 5 to 15% of all breast and ovarian cancers. In recent years knowledge of risk genes, epigenetic factors and tumorigenesis and its clinical impact has increased dramatically. The growing body of information, its ready availability for lay people and its potential consequences bring genetic counseling into focus. In the 17 centers of the German Consortium of Hereditary Breast and Ovarian Cancer (GC-HBOC) counselees receive individual and comprehensive counseling as well as genetic testing. Counseling aims to enable counselees to make preference-sensitive decisions, as well as to educate them on what individual risk reduction strategies are available. Currently, regional networks of cooperation partners of GC-HBOC are set up. This transsectoral approach will make counseling and diagnostic testing more easily accessible to patients who do not live close to a GC-HBOC center.

CME Prakt Fortbild Gynakol Geburtsmed Gynakol Endokrinol 2017; 13(2): 170–186

Keywords
Hereditary breast and ovarian cancer, individual counseling, genetic testing, preference-sensitive decision

Dorothee Speiser
Klinik für Gynäkologie mit Brustzentrum, Zentrum für Familiären
Brust- und Eierstockkrebs Berlin, Charité – Universitätsmedizin Berlin
Reviewer: Björn Lisboa, Duisburg,
und Alma-Verena Rausch, Hamburg

Speiser D. Beratung ... Gynakol Geburtsmed Gynakol Endokrinol 2017; 13(2): 170–186 publiziert 31.07.2017 www.akademos.de/gyn ©akademos Wissenschaftsverlag 2017 ISSN 1614-8533