In cooperation with


Down-Screening - NT-Messung und neue Methoden der Risikoabschätzung (Integrated- und Sequential-Test)

Within the last 15 years a number of Down screening tests such as the first trimester Combined Test, the second trimester Quadruple Test, and the Integrated Test have been introduced. Screening using the first trimester Combined Test techniques is now widely offered to women despite the uncertainty about which screening method should be used in practice. The Serum, Urine and Ultrasound Screening Study (SURUSS) and the First And Second Trimester Evaluation of Risks (FASTER) study have recently addressed the issue which of these different tests yields the best detection rate for the least number of invasive tests. The practical impacts of their results on Down Screening are discussed in this brief review.

Holger Lebek, Charles Rodeck, Katrin Kalache,
Karim D. Kalache

Reviewer: Bernd-Joachim Hackelöer, Hamburg
und Boris Tutschek, München

CME Prakt Fortbild Gynakol Geburtsmed Gynakol Endokrinol 2007;3(2):26-36