In cooperation with


Fertility protection in women exposed to chemo- and radiotherapy

Increasing survival rates in cancer and the growing interest in life quality after cancer therapy has put fertility protection into the focus of attention. In many cancer therapies such as radiation of the pelvis, high dosage chemotherapy in hodgkin disease and breast cancer, bone marrow transplantation and others, the risk of developing secondary amenorrhoea and very early premature ovarian failure can reach 50% and more.Therefore, all young patients up to 35-40 years of age receiving cytotoxic therapies should be counselled by experienced specialists in reproductive medicine in an interdisciplinary setting.The patients can be offered cryopreservation of fertilized and unfertilized oocytes, cryopreservation of ovarian tissue and possibly GnRHanalogues. As the choice of the ideal technique is very complex and as some of the techniques are still experimental, counselling can only offered by trained specialists.The network FertiPROTEKT has been established in 2006 to offer profound information about this topic to patients and doctors to optimize all available fertility preserving techniques and to set up a network of specialized centres that offer nationwide counselling of patients. A list of the trained centres and comprehensive information about this topic can be found on the homepage of the network (

Michael von Wolff
Universitäts-Frauenklinik Heidelberg, Abteilung für Gynäkologische
Endokrinologie und Fertilitätsstörungen, Heidelberg

Reviewer: Sören von Otte, Lübeck
und Gülten Oskay-Özcelik, Berlin

CME Prakt Fortbild Gynakol Geburtsmed Gynakol
Endokrinol 2008; 4(1): 12-23